FM26
FM26 is a potent, allosteric inverse agonist of RORγt (IC50 = 264 nM) featuring a distinct isoxazole chemotype. It effectively suppresses IL-17A mRNA in EL4 cells in vitro and serves as a valuable tool for investigating Th17 cell biology and autoimmune disease pathways in research settings.
Product Specifications
CAS Number
2407981-35-3
Field of Research
Metabolism Research
Smiles
C (NC1=CC=C (C (O) =O) C=C1) C=2C (=NOC2C=3C=CNC3) C4=C (C (F) (F) F) C=CC=C4Cl
Molecular Formula
C22H15ClF3N3O3
Molecular Weight
461.82
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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