GBR 12783
GBR 12783 is a highly selective dopamine reuptake inhibitor, enhancing memory and hippocampal acetylcholine release in rats. It potently inhibits dopamine uptake in striatal synaptosomes (IC50 ~1.5 nM), making it a valuable research tool for studying dopaminergic pathways in neuropharmacology and behavioral models.
Product Specifications
CAS Number
67469-57-2
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
Cl.Cl.C (CN1CCN (C\C=C\c2ccccc2) CC1) OC (c1ccccc1) c1ccccc1
Molecular Formula
C28H32N2O
Molecular Weight
412.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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