GC 14
GC-14 is a potent and selective antagonist of human thyroid hormone receptors, demonstrating higher affinity for the hTRβ subtype (IC50 = 35 nM) than for hTRα (IC50 = 200 nM) . This small molecule is a valuable research tool for investigating thyroid hormone signaling in metabolic studies, cardiac function, and central nervous system research using both cellular and animal models.
Product Specifications
CAS Number
447415-34-1
Field of Research
Metabolism Research
Smiles
OC1=C (C=C (CC2=C (C) C=C (OCC (O) =O) C=C2C) C=C1C (C) C) C3=CC=C (N (=O) =O) C=C3
Molecular Formula
C26H27NO6
Molecular Weight
449.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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