GDC-0276
GDC-0276 is a potent and selective oral inhibitor of the voltage-gated sodium channel NaV1.7. It serves as a valuable research tool for investigating pain pathways and has demonstrated efficacy in preclinical models of neuropathic and inflammatory pain.
Product Specifications
CAS Number
1494581-70-2
Product Name Alternative
GDC0276, GDC-0276, GDC 0276, NaV1.7 Electrophysiology, RG7893, RG-7893
Field of Research
Pharmacology & Drug Discovery
Purity
98.94% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:5 mg/mL (10.81 mM) ; DMSO:100 mg/mL (216.18 mM)
Smiles
O=C (NS (=O) (=O) N1CCC1) C=2C=C (C (OCC34CC5CC (CC (C5) C3) C4) =CC2F) C6CC6
Molecular Formula
C24H31FN2O4S
Molecular Weight
462.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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