Gemilukast
Gemilukast (ONO-6950) is an orally bioavailable, potent dual antagonist of the CysLT1 and CysLT2 receptors. It blocks leukotriene-induced bronchoconstriction and is utilized in preclinical asthma research, including in vitro receptor studies and in vivo models of airway inflammation.
Product Specifications
CAS Number
1232861-58-3
Product Name Alternative
CysLT2, CysLTR, CysLT1, Gemilukast, ONO 6950, ONO6950, ONO-6950
Field of Research
Pharmacology & Drug Discovery
Purity
98.21% (May vary between batches)
Solubility
DMSO:100 mg/mL (166.2 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6.65 mM)
Smiles
Cc1c (CCCC (O) =O) c2c (F) ccc (C#Cc3ccc (OCCCCc4cccc (F) c4C) cc3) c2n1CCCC (O) =O
Molecular Formula
C36H37F2NO5
Molecular Weight
601.68
Storage Conditions
-20°C
Notes
For research use only.
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