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Gemilukast

Gemilukast (ONO-6950) is an orally bioavailable, potent dual antagonist of the CysLT1 and CysLT2 receptors. It blocks leukotriene-induced bronchoconstriction and is utilized in preclinical asthma research, including in vitro receptor studies and in vivo models of airway inflammation.

Product Specifications

CAS Number

1232861-58-3

Product Name Alternative

CysLT2, CysLTR, CysLT1, Gemilukast, ONO 6950, ONO6950, ONO-6950

Field of Research

Pharmacology & Drug Discovery

Purity

98.21% (May vary between batches)

Solubility

DMSO:100 mg/mL (166.2 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6.65 mM)

Smiles

Cc1c (CCCC (O) =O) c2c (F) ccc (C#Cc3ccc (OCCCCc4cccc (F) c4C) cc3) c2n1CCCC (O) =O

Molecular Formula

C36H37F2NO5

Molecular Weight

601.68

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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