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IPN60090

IPN60090 is a potent and orally bioavailable specific inhibitor of renal-type glutaminase (GLS1) with an IC50 of 31 nM. It is a research tool for studying cancer metabolism and immunomodulation, with applications in both in vitro enzymatic assays and in vivo preclinical models of GLS1-mediated diseases.

Product Specifications

CAS Number

1853164-83-6

Product Name Alternative

Glutaminase GLS1 (KGA), GLS1, GLS1-IN-1, IPN60090, IPN-60090, IPN 60090

Field of Research

Metabolism Research, Protein Biochemistry

Purity

99.76% (May vary between batches)

Solubility

DMSO:27.5 mg/mL (51.64 mM) ;10% DMSO+90% Corn Oil:2 mg/mL (3.76 mM)

Smiles

CNC (=O) c1cn (C[C@H] (F) CCc2ccc (NC (=O) Cc3cc (OC4CC (F) (F) C4) cc (C) n3) nn2) nn1

Molecular Formula

C24H27F3N8O3

Molecular Weight

532.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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