GNE-616
GNE-616 is a potent, selective, and orally bioavailable small molecule inhibitor of the human Nav1.7 sodium channel (Ki: 0.79 nM) . It is a metabolically stable research compound used in preclinical studies for chronic pain, supporting both in vitro electrophysiology and in vivo pain model experiments.
Product Specifications
CAS Number
2349371-81-7
Field of Research
Pharmacology & Drug Discovery
Smiles
C (F) (F) (F) [C@@H]1C[C@@H] (N (CC1) [C@@H]2C=3C (=CC (S (NC=4C=CN=CN4) (=O) =O) =C (F) C3) OCC2) C5=CC=CC=N5
Molecular Formula
C24H23F4N5O3S
Molecular Weight
537.53
Storage Conditions
-20°C
Notes
For research use only.
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