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GNF-6231

GNF-6231 is an orally active, selective small molecule inhibitor of Porcupine (PORCN), effectively suppressing Wnt pathway signaling. It is utilized in both in vitro and in vivo research to investigate Wnt-driven biological processes and diseases, including cancer and tissue regeneration.

Product Specifications

CAS Number

1243245-18-2

Product Name Alternative

Porcupine, GNF 6231, GNF6231, GNF-6231

Field of Research

Signal Transduction, Stem Cell & Developmental Biology

Purity

99.54% (May vary between batches)

Solubility

DMSO:36 mg/mL (80.27 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (5.57 mM)

Smiles

CC (=O) N1CCN (CC1) c1ccc (NC (=O) Cc2cnc (c (C) c2) -c2ccnc (F) c2) nc1

Molecular Formula

C24H25FN6O2

Molecular Weight

448.49

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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