GSK 366
GSK 366 is a highly potent and selective inhibitor of kynurenine-3-monooxygenase (KMO), exhibiting IC50 values of 0.7 nM and 2.3 nM against the bacterial and human enzymes, respectively. This small molecule is a valuable research tool for investigating the kynurenine pathway in models of neurodegenerative and inflammatory diseases, both in vitro and in vivo.
Product Specifications
CAS Number
1953157-39-5
Field of Research
Metabolism Research
Smiles
C[C@@H] (Oc1cc2onc (CCC (O) =O) c2cc1Cl) c1ccc (C) nn1
Molecular Formula
C17H16ClN3O4
Molecular Weight
361.78
Storage Conditions
-20°C
Notes
For research use only.
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