GSK2593074A
GSK2593074A (GSK'074) is a small molecule inhibitor of RIP1 and RIP3 kinases, functioning as a potent inhibitor of necroptosis. It is a valuable research tool for studying programmed necrosis in both cellular models and animal studies, applicable in fields like inflammation, neurodegenerative diseases, and ischemia-reperfusion injury.
Product Specifications
CAS Number
1337531-06-2
Product Name Alternative
RIPkinase, RIP3, RIP1, RIP kinase, GSK'074, GSK2593074A, GSK-2593074A
Field of Research
Cell Biology, Signal Transduction
Purity
99.78% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.3 mM) ; DMSO:41.67 mg/mL (89.5 mM)
Smiles
Cn1cc (cn1) -c1cnc (N) c2c (csc12) -c1ccc2N (CCc2c1) C (=O) Cc1ccccc1
Molecular Formula
C27H23N5OS
Molecular Weight
465.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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