Fiboflapon sodium
Fiboflapon sodium (GSK2190915) is a potent and orally active inhibitor of 5-lipoxygenase-activating protein (FLAP), exhibiting a 2.9 nM binding affinity and an IC50 of 76 nM for LTB4 inhibition in human whole blood. This FLAP inhibitor is a valuable research tool for investigating leukotriene biosynthesis in inflammatory pathways, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1196070-26-4
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
[Na].CCOc1ccc (cn1) -c1ccc (Cn2c (CC (C) (C) C (O) =O) c (SC (C) (C) C) c3cc (OCc4ccc (C) cn4) ccc23) cc1
Molecular Formula
C38H43N3NaO4S
Molecular Weight
660.83
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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