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GSK3368715 dihydrochloride

GSK3368715 dihydrochloride is a potent, orally bioavailable pan-inhibitor of type I PRMT enzymes (PRMT1, 3, 4, 6, 8) . It exhibits anticancer activity and is a valuable chemical probe for investigating PRMT biology in both cellular assays and in vivo models of advanced solid tumors.

Product Specifications

CAS Number

1628925-77-8

Product Name Alternative

Histone Methyltransferase, HistoneMethyltransferase, GSK 3368715, GSK 3368715 Dihydrochloride, GSK3368715, GSK-3368715, GSK3368715 2HCl, GSK3368715 Dihydrochloride, GSK-3368715 Dihydrochloride, EPZ019997, EPZ-019997, EPZ019997 2HCl, EPZ019997 dihydrochloride, EPZ-019997 Dihydrochloride, EPZ 019997 Dihydrochloride, EPZ 019997, PRMT8, PRMT4, PRMT6, PRMT3, PRMT1

Field of Research

Epigenetics & Chromatin

Purity

99.66% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.1 mM) ; H2O:100 mg/mL (227.55 mM) ; DMSO:100 mg/mL (227.55 mM)

Smiles

Cl.Cl.CCOCC1 (COCC) CCC (CC1) c1n[nH]cc1CN (C) CCNC

Molecular Formula

C20H40Cl2N4O2

Molecular Weight

439.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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