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GW274150

GW274150 is a potent, orally bioavailable, and selective dual inhibitor of human and rat inducible nitric oxide synthase (iNOS), exhibiting high selectivity over eNOS and nNOS. It has demonstrated protective efficacy in vivo models of acute lung injury, supporting its research application in studying inflammatory diseases.

Product Specifications

CAS Number

210354-22-6

Product Name Alternative

NNOS, iNOS, eNOS, human eNOS, human nNOS, human iNOS, GW 274150, GW274150, GW-274150, rat nNOS, rat iNOS

Field of Research

Immunology & Inflammation

Purity

96.43% (May vary between batches)

Solubility

H2O:50 mg/mL (228 mM) ; DMSO:< 1 mg/mL (insoluble or slightly soluble)

Smiles

C ([C@@H] (C (O) =O) N) CSCCNC (C) =N

Molecular Formula

C8H17N3O2S

Molecular Weight

219.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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