GW311616 hydrochloride
GW-311616 hydrochloride is a potent, selective, and orally active inhibitor of human neutrophil elastase (HNE), exhibiting an IC50 of 22 nM and a Ki of 0.31 nM. Its extended duration of action supports its investigation in preclinical models of inflammatory and pulmonary diseases, such as chronic obstructive pulmonary disease (COPD) and bronchiectasis.
Product Specifications
CAS Number
197890-44-1
Field of Research
Protein Biochemistry
Smiles
Cl.[H][C@@]12CCN (C (=O) \C=C\CN3CCCCC3) [C@@]1 ([H]) [C@H] (C (C) C) C (=O) N2S (C) (=O) =O
Molecular Formula
C19H32ClN3O4S
Molecular Weight
433.99
Storage Conditions
-20°C
Notes
For research use only.
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