HPN-01
HPN-01 (IKK inhibitor XII) is a selective inhibitor of IKK-α, IKK-β, and IKK-ε. It has demonstrated efficacy in an experimental autoimmune encephalomyelitis (EAE) mouse model, reducing disease severity, modulating immune responses, and extending lifespan, making it a valuable tool for studying autoimmune and inflammatory disorders.
Product Specifications
CAS Number
928655-63-4
Product Name Alternative
IκB, IKK-ε, IKK, IKK-α, IKK-β, IkB, IkB/IKK, HPN 01, HPN01, HPN-01
Field of Research
Signal Transduction
Purity
98.07% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.21 mM) ; DMSO:80 mg/mL (199.07 mM)
Smiles
NC (=O) c1cc (cc (c1N) -c1ccc (cc1) S (N) (=O) =O) -c1ccc (Cl) cc1
Molecular Formula
C19H16ClN3O3S
Molecular Weight
401.87
Storage Conditions
-20°C
Notes
For research use only.
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