Ilorasertib hydrochloride
Ilorasertib hydrochloride is a potent, ATP-competitive inhibitor targeting Aurora kinases (A, B, C) and other kinases including RET and PDGFRβ. It is utilized in cancer research to study cell cycle progression and tumorigenesis in both cellular and animal models.
Product Specifications
CAS Number
1847485-91-9
Product Name Alternative
FLT3, Ilorasertib hydrochloride, Ilorasertib Hydrochloride, c-KIT, CSF-1R, ABT 348 Hydrochloride, ABT348 Hydrochloride, ABT-348 Hydrochloride, ABT-348 hydrochloride, Aurora A, Aurora B, Aurora B (Y156H), Aurora C, Aurora Kinase, AuroraKinase, PDGFRβ, PDGFRα, VEGFR1, VEGFR2, VEGFR3
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction
Purity
98.34% (May vary between batches)
Solubility
DMSO:41.67 mg/mL (79.37 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.81 mM)
Smiles
Cl.Nc1ncc (-c2cnn (CCO) c2) c2scc (-c3ccc (NC (=O) Nc4cccc (F) c4) cc3) c12
Molecular Formula
C25H22ClFN6O2S
Molecular Weight
525
Storage Conditions
-20°C
Notes
For research use only.
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