INCB 3284 dimesylate
INCB 3284 dimesylate is a potent, selective, and orally active antagonist of the human CCR2 receptor, blocking MCP-1 binding with an IC50 of 3.7 nM. It has been utilized in research models of acute liver failure and inflammation, demonstrating efficacy in both in vitro cellular assays and in vivo preclinical studies.
Product Specifications
CAS Number
887401-93-6
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery
Smiles
CS (=O) (O) =O.O[C@]1 (C2=CN=C (OC) C=C2) CC[C@] (N3C[C@@H] (CC3) NC (CNC (C4=CC (C (F) (F) F) =CC=C4) =O) =O) ([H]) CC1.CS (=O) (O) =O
Molecular Formula
C28H39F3N4O10S2
Molecular Weight
712.76
Storage Conditions
-20°C
Notes
For research use only.
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