INCB 3284
INCB 3284 is a potent, selective, and orally bioavailable antagonist of the human CCR2 receptor, blocking its interaction with MCP-1. It is a valuable research tool for investigating CCR2-mediated pathways in inflammatory diseases and has been utilized in preclinical studies, including models of hemorrhagic shock.
Product Specifications
CAS Number
887401-92-5
Product Name Alternative
INCB 3284, INCB3284, INCB-3284, MCP-1-hCCR2, CCR2
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
97.81% (May vary between batches)
Solubility
DMSO:60 mg/mL (115.26 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.84 mM) ; H2O:< 0.1 mg/mL (insoluble)
Smiles
COc1ccc (cn1) [C@@]1 (O) CC[C@@H] (CC1) N1CC[C@H] (C1) NC (=O) CNC (=O) c1cccc (c1) C (F) (F) F
Molecular Formula
C26H31F3N4O4
Molecular Weight
520.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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