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(R)-Trolox

Product Specifications

UNSPSC Description

(R)-Trolox is a vitamin E analogue and a competitive tyrosinase inhibitor with a Ki value of 0.83 mM and a ID50 value of 1.88 mM[1]. The (R)-Trolox has stronger tyrosinase affinity than the (S) enantiomer (Ki value of 0.61 mM)[1].

Target Antigen

Tyrosinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/r-trolox.html

Purity

99.91

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=C([C@@]1(C)CCC2=C(C)C(O)=C(C)C(C)=C2O1)O

Molecular Weight

250.294

References & Citations

[1]Yu L. Inhibitory effects of (S)- and (R)-6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acids on tyrosinase activity. J Agric Food Chem. 2003 Apr 9;51(8):2344-7.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-101445A/R-Trolox-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-101445A/R-Trolox-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

53101-49-8

Available Sizes

Curated Selection

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