(R) -Trolox
(R) -Trolox is a vitamin E analogue and a competitive tyrosinase inhibitor with a Ki value of 0.83 mM and a ID50 value of 1.88 mM[1]. The (R) -Trolox has stronger tyrosinase affinity than the (S) enantiomer (Ki value of 0.61 mM) [1].
Product Specifications
CAS Number
[53101-49-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Tyrosinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-trolox.html
Purity
99.80
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C([C@@]1(C)CCC2=C(C)C(O)=C(C)C(C)=C2O1)O
Molecular Formula
C14H18O4
Molecular Weight
250.29
Precautions
H302, H315, H319, H335
References & Citations
[1]Yu L. Inhibitory effects of (S) - and (R) -6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acids on tyrosinase activity. J Agric Food Chem. 2003 Apr 9;51 (8) :2344-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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