(R) -Trolox

(R) -Trolox is a vitamin E analogue and a competitive tyrosinase inhibitor with a Ki value of 0.83 mM and a ID50 value of 1.88 mM[1]. The (R) -Trolox has stronger tyrosinase affinity than the (S) enantiomer (Ki value of 0.61 mM) [1].

Product Specifications

CAS Number

[53101-49-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Tyrosinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/r-trolox.html

Purity

99.80

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=C([C@@]1(C)CCC2=C(C)C(O)=C(C)C(C)=C2O1)O

Molecular Formula

C14H18O4

Molecular Weight

250.29

Precautions

H302, H315, H319, H335

References & Citations

[1]Yu L. Inhibitory effects of (S) - and (R) -6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acids on tyrosinase activity. J Agric Food Chem. 2003 Apr 9;51 (8) :2344-7.