INT-767
INT-767 is a potent dual agonist of the farnesoid X receptor (FXR) and TGR5, developed for NASH research. It has demonstrated efficacy in preclinical models, preventing steatohepatitis and promoting the browning of visceral adipose tissue alongside enhanced mitochondrial function in both in vitro and in vivo studies.
Product Specifications
CAS Number
1000403-03-1
Product Name Alternative
INT 767, INT767, INT-767, FXR, TGR5
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Purity
98.00% (May vary between batches)
Solubility
DMSO:80 mg/mL (161.73 mM) ; H2O:80 mg/mL (161.73 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.67 mM)
Smiles
O[C@H]1[C@]2 ([H]) [C@@] (CC[C@]3 ([C@@]2 ([H]) CC[C@]3 ([H]) [C@H] (C) CCOS (=O) ([O-]) =O) C) ([H]) [C@@]4 ([C@] (C[C@@H] (CC4) O) ([H]) [C@H]1CC) C.[Na+]
Molecular Formula
C25H43NaO6S
Molecular Weight
494.66
Storage Conditions
-20°C
Notes
For research use only.
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