IT1t dihydrochloride
IT1t dihydrochloride is a potent CXCR4 antagonist that disrupts the CXCL12/CXCR4 interaction with an IC50 of 2.1 nM. This small molecule is a valuable research tool for studying cancer metastasis, stem cell mobilization, and HIV-1 infection in both in vitro and in vivo models.
Product Specifications
CAS Number
1092776-63-0
Product Name Alternative
CXCL12, CXCL12/CXCR4, CXCR4, HIV-1 (X4), IT1t Dihydrochloride, IT1t dihydrochloride, IT-1t dihydrochloride, IT1t
Field of Research
Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
98.03% (May vary between batches)
Solubility
DMSO:27 mg/mL (56.3 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.09 mM)
Smiles
Cl.Cl.CC1 (C) CN2C (CS\C (NC3CCCCC3) =N/C3CCCCC3) =CSC2=N1
Molecular Formula
C21H36Cl2N4S2
Molecular Weight
479.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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