JAK-IN-1
JAK-IN-1 is a potent, cell-permeable inhibitor of JAK kinases, demonstrating a favorable selectivity profile with IC50 values of 0.26 nM (JAK1), 0.8 nM (JAK2), and 3.2 nM (JAK3) . It is a valuable chemical tool for investigating JAK-STAT signaling in cellular and biochemical assays relevant to immunology and oncology research.
Product Specifications
CAS Number
1334673-53-8
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
CC (C) (C) [C@@H] (NC (=O) c1c[nH]c2ncc (nc12) C1CC1) C (=O) N1CC (C1) C#N
Molecular Formula
C20H24N6O2
Molecular Weight
380.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
