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Jaspamycin

Jaspamycin (7-CN-7-C-Ino) is a potent activator of Protein Kinase A (PKA) in Trypanosoma brucei, binding the regulatory subunit with high affinity (Kd ~8 nM) . It exhibits anti-parasitic activity, making it a valuable research tool for studying kinetoplastid biology and cAMP signaling pathways in vitro.

Product Specifications

CAS Number

22242-96-2

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Infectious Disease & Virology, Signal Transduction, Stem Cell & Developmental Biology

Smiles

O[C@H]1[C@H] (N2C3=C (C (C#N) =C2) C (=O) N=CN3) O[C@H] (CO) [C@H]1O

Molecular Formula

C12H12N4O5

Molecular Weight

292.25

Storage Conditions

-20°C

Notes

For research use only.

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