JHU395
JHU395 is a stable, orally-bioavailable prodrug of the glutamine antagonist DON. It effectively delivers DON to malignant peripheral nerve sheath tumors (MPNSTs), demonstrating significant antitumor activity in both in vitro and in vivo models for cancer metabolism research.
Product Specifications
CAS Number
2079938-92-2
Product Name Alternative
GA, JHU 395, JHU395, JHU-395, Apoptosis
Field of Research
Cell Biology
Purity
99.15% (May vary between batches)
Solubility
DMSO:90 mg/mL (201.13 mM) ;10% DMSO+90% Corn Oil:3.3 mg/mL (7.37 mM)
Smiles
C (OC (C (C) (C) C) =O) (OC (N[C@H] (C (OC (C) C) =O) CCC (C=[N+]=[N-]) =O) =O) C1=CC=CC=C1
Molecular Formula
C22H29N3O7
Molecular Weight
447.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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