Tarlox-TKI
Tarlox-TKI is the active kinase inhibitor component of Tarloxotinib, functioning as a pan-ErbB inhibitor. It demonstrates antitumor activity by inhibiting NRG1 and suppressing HER2 mutants, making it a valuable tool for in vitro and in vivo cancer research targeting ErbB-driven pathways.
Product Specifications
CAS Number
2135696-72-7
Product Name Alternative
ErbB, Kinase, Kinase inhibitor-1, Tarlox TKI, TarloxTKI, Tarlox-TKI
Field of Research
Cardiovascular Research, Signal Transduction
Purity
97.03% (May vary between batches)
Solubility
DMSO:80 mg/mL (173.26 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.15 mM)
Smiles
CN (C) C\C=C\C (=O) Nc1cc2c (Nc3ccc (Cl) c (Br) c3) ncnc2cn1
Molecular Formula
C19H18BrClN6O
Molecular Weight
461.74
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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