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Tarlox-TKI

Tarlox-TKI is the active kinase inhibitor component of Tarloxotinib, functioning as a pan-ErbB inhibitor. It demonstrates antitumor activity by inhibiting NRG1 and suppressing HER2 mutants, making it a valuable tool for in vitro and in vivo cancer research targeting ErbB-driven pathways.

Product Specifications

CAS Number

2135696-72-7

Product Name Alternative

ErbB, Kinase, Kinase inhibitor-1, Tarlox TKI, TarloxTKI, Tarlox-TKI

Field of Research

Cardiovascular Research, Signal Transduction

Purity

97.03% (May vary between batches)

Solubility

DMSO:80 mg/mL (173.26 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.15 mM)

Smiles

CN (C) C\C=C\C (=O) Nc1cc2c (Nc3ccc (Cl) c (Br) c3) ncnc2cn1

Molecular Formula

C19H18BrClN6O

Molecular Weight

461.74

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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