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Eltanexor Z-isomer

The Z-isomer of Eltanexor is the less active form of the CRM1 inhibitor KPT-8602. It demonstrates variable potency in vitro, with IC50 values ranging from 30 μM in 3T3 fibroblasts. This selective inhibitor is used in cancer research, particularly for studying hematological malignancies in cellular models.

Product Specifications

CAS Number

1642300-78-4

Field of Research

Pharmacology & Drug Discovery

Smiles

NC (=O) C (=C/n1cnc (n1) -c1cc (cc (c1) C (F) (F) F) C (F) (F) F) \c1cncnc1

Molecular Formula

C17H10F6N6O

Molecular Weight

428.29

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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