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L-Eflornithine

L-Eflornithine is the L-enantiomer of eflornithine and acts as an irreversible inhibitor of ornithine decarboxylase (ODC), exhibiting a KD of 1.3±0.3 μM and a Kinact of 0.15±0.03 min−1. This compound is a research tool for studying polyamine biosynthesis and has been investigated in models of trypanosomiasis and cancer, both in vitro and in vivo.

Product Specifications

CAS Number

66640-93-5

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery

Smiles

[C@@] (CCCN) (C (F) F) (C (O) =O) N

Molecular Formula

C6H12F2N2O2

Molecular Weight

182.17

Storage Conditions

-20°C

Notes

For research use only.

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