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Lp-PLA2-IN-3

Lp-PLA2-IN-3 is a potent, orally bioavailable inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2), demonstrating an IC50 of 14 nM against the recombinant human enzyme. This small molecule is a valuable research tool for investigating Lp-PLA2's role in cardiovascular and neurodegenerative diseases in both cellular and animal models.

Product Specifications

CAS Number

2196245-16-4

Product Name Alternative

Lp PLA2 IN 3, Lp-PLA2, LpPLA2IN3, Lp-PLA-2-IN-3, Lp-PLA2-IN-3

Field of Research

Metabolism Research

Purity

99.49% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.69 mM) ; DMSO:250 mg/mL (534.36 mM)

Smiles

Nc1ccc (cc1) S (=O) (=O) Nc1ccc (Oc2ccc (Cl) c (c2) C (F) (F) F) c (c1) C#N

Molecular Formula

C20H13ClF3N3O3S

Molecular Weight

467.85

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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