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LpxH-IN-AZ1

LpxH-IN-AZ1 is a potent sulfonylpiperazine inhibitor of the bacterial enzyme LpxH, a UDP-2,3-diacylglucosamine pyrophosphate hydrolase. It demonstrates antimicrobial activity, particularly against Klebsiella pneumoniae with an IC50 of 0.36 μM, making it a valuable tool for studying lipopolysaccharide biosynthesis in Gram-negative pathogens.

Product Specifications

CAS Number

901260-40-0

Product Name Alternative

LpxH IN AZ1, LpxHINAZ1, LpxH-IN-AZ1, LpxH-IN-AZ-1, Bacterial

Field of Research

Infectious Disease & Virology

Purity

99.26% (May vary between batches)

Solubility

DMSO:4.54 mg/mL (10.01 mM)

Smiles

C (C) (=O) N1C=2C (=CC (S (=O) (=O) N3CCN (CC3) C4=CC (C (F) (F) F) =CC=C4) =CC2) CC1

Molecular Formula

C21H22F3N3O3S

Molecular Weight

453.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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