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LSN 3213128

LSN 3213128 is an orally active, nonclassical antifolate that selectively inhibits AICARFT with high potency (IC50 = 16 nM) . Its anti-tumor activity has been investigated in preclinical models, where it disrupts de novo purine biosynthesis, making it a research tool for studying metabolic oncology and hematological cancers.

Product Specifications

CAS Number

1941211-99-9

Field of Research

Cell Biology, Immunology & Inflammation

Smiles

O[C@@H]1CCN (C1) c1ccc (s1) S (=O) (=O) Nc1cc2c (cc[nH]c2=O) cc1F

Molecular Formula

C17H16FN3O4S2

Molecular Weight

409.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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