LSN 3213128
LSN 3213128 is an orally active, nonclassical antifolate that selectively inhibits AICARFT with high potency (IC50 = 16 nM) . Its anti-tumor activity has been investigated in preclinical models, where it disrupts de novo purine biosynthesis, making it a research tool for studying metabolic oncology and hematological cancers.
Product Specifications
CAS Number
1941211-99-9
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
O[C@@H]1CCN (C1) c1ccc (s1) S (=O) (=O) Nc1cc2c (cc[nH]c2=O) cc1F
Molecular Formula
C17H16FN3O4S2
Molecular Weight
409.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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