Mcl1-IN-11
Mcl1-IN-11 (Compound G) is a potent and selective Mcl-1 inhibitor, demonstrating a Ki of 0.06 μM for Mcl-1 versus 4.2 μM for Bcl-2. This small molecule is a valuable chemical probe for investigating Mcl-1-dependent apoptosis in cancer research, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2042211-13-0
Field of Research
Cell Biology
Smiles
CC1 (C) C=2C (=CC (C) =C (C (=C) C3=CC=C (C (NS (=O) (=O) C4=CC (N (=O) =O) =C (NCCSC5=CC=CC=C5) C=C4) =O) C=C3) C2) C (C) (C) CC1
Molecular Formula
C38H41N3O5S2
Molecular Weight
683.88
Storage Conditions
-20°C
Notes
For research use only.
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