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PPARγ agonist 14

PPARγ agonist 14 (compound 3) is a PPARy agonist (EC50=2.4 μM) with anti-diabetic activity. PPARγ agonist 14 can improve intracellular glucose uptake, promote insulin release, and lower blood sugar. In addition, PPARγ agonist 14 also improves mitochondrial function, reduces oxidative stress, and inhibits inflammatory factors. PPARγ agonist 14 can be used in the study of neurodegenerative diseases, neuroinflammatory diseases, and other diseases[1].

Product Specifications

CAS Number

6951-57-1

UNSPSC

12352005

Target

PPAR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Field of Research

Metabolic Disease; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/pparγ-agonist-14.html

Purity

98.0

Smiles

O=C1C2=C(OC)C(O)=C(OC)C=C2OC(C1)C3=CC=C(C=C3)O

Molecular Formula

C17H16O6

Molecular Weight

316.31

References & Citations

[1]Jianfeng Zhou; et al. Novel application of flavanone compound. CN106580951. 2016-11-17

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PPARγ

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