PPARγ agonist 14
PPARγ agonist 14 (compound 3) is a PPARy agonist (EC50=2.4 μM) with anti-diabetic activity. PPARγ agonist 14 can improve intracellular glucose uptake, promote insulin release, and lower blood sugar. In addition, PPARγ agonist 14 also improves mitochondrial function, reduces oxidative stress, and inhibits inflammatory factors. PPARγ agonist 14 can be used in the study of neurodegenerative diseases, neuroinflammatory diseases, and other diseases[1].
Product Specifications
CAS Number
6951-57-1
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pparγ-agonist-14.html
Purity
98.0
Smiles
O=C1C2=C(OC)C(O)=C(OC)C=C2OC(C1)C3=CC=C(C=C3)O
Molecular Formula
C17H16O6
Molecular Weight
316.31
References & Citations
[1]Jianfeng Zhou; et al. Novel application of flavanone compound. CN106580951. 2016-11-17
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PPARγ
Frequently Asked Questions
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