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Methyllycaconitine citrate

Methyllycaconitine citrate (MLA) is a potent and selective antagonist of the α7 nicotinic acetylcholine receptor (α7nAChR) with the ability to cross the blood-brain barrier. It is widely used as a pharmacological tool in neuroscience research to investigate receptor function in both in vitro binding assays and in vivo behavioral studies.

Product Specifications

CAS Number

351344-10-0

Product Name Alternative

α7 nAChR, MLA

Field of Research

Neuroscience

Purity

98.03% (May vary between batches)

Solubility

H2O:1 mg/mL (1.14 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (4.57 mM) ; DMSO:100 mg/mL (114.3 mM)

Smiles

OC (=O) CC (O) (CC (O) =O) C (O) =O.[H][C@]12C[C@]3 ([H]) [C@] ([H]) ([C@H]1OC) [C@] (O) (C[C@@H]2OC) C1 (O) [C@@H] (OC) [C@@]2 ([H]) C33C1N (CC) C[C@]2 (COC (=O) c1ccccc1N1C (=O) C[C@H] (C) C1=O) CC[C@@H]3OC

Molecular Formula

C43H58N2O17

Molecular Weight

874.92

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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