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MK-7145

MK-7145 is a potent and selective small-molecule inhibitor of the renal outer medullary potassium channel (ROMK), exhibiting an IC50 of 45 nM. It serves as a valuable pharmacological tool for investigating renal electrolyte balance, blood pressure regulation, and diuretic mechanisms in both cellular and animal models.

Product Specifications

CAS Number

1255204-84-2

Field of Research

Pharmacology & Drug Discovery

Smiles

CC1=C2C (C (=O) OC2) =CC=C1[C@H] (CN3CCN (C[C@H] (O) C=4C (C) =C5C (=CC4) C (=O) OC5) CC3) O

Molecular Formula

C26H30N2O6

Molecular Weight

466.53

Storage Conditions

-20°C

Notes

For research use only.

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