MK-7145
MK-7145 is a potent and selective small-molecule inhibitor of the renal outer medullary potassium channel (ROMK), exhibiting an IC50 of 45 nM. It serves as a valuable pharmacological tool for investigating renal electrolyte balance, blood pressure regulation, and diuretic mechanisms in both cellular and animal models.
Product Specifications
CAS Number
1255204-84-2
Field of Research
Pharmacology & Drug Discovery
Smiles
CC1=C2C (C (=O) OC2) =CC=C1[C@H] (CN3CCN (C[C@H] (O) C=4C (C) =C5C (=CC4) C (=O) OC5) CC3) O
Molecular Formula
C26H30N2O6
Molecular Weight
466.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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