N-Desethyl Sunitinib
Sunitinib is an oral multi-tyrosine kinase inhibitor targeting VEGFR, PDGFR, KIT, and FLT3, used in advanced renal cell carcinoma. Its primary active metabolite, N-Desethyl Sunitinib (SU012662), is formed via CYP3A4 metabolism and is utilized in pharmacokinetic and efficacy studies both in vitro and in vivo.
Product Specifications
CAS Number
356068-97-8
Product Name Alternative
SU11662, SU-11662, SU12662, SU-12662, SU 11662, SU 12662, PDGFRβ, VEGFR, NDesethyl Sunitinib, N-Desethyl Sunitinib, N Desethyl Sunitinib, Inhibitor, KIT, inhibit, cKit
Field of Research
Cardiovascular Research, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Solubility
DMSO:4 mg/mL (10.8 mM)
Smiles
C (=C\1/C=2C (NC1=O) =CC=C (F) C2) \C3=C (C) C (C (NCCNCC) =O) =C (C) N3
Molecular Formula
C20H23FN4O2
Molecular Weight
370.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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