Wnt/β-catenin agonist 1

Wnt/β-catenin agonist 1 (compound 3f) is a Wnt/β-catenin signalling pathway agonist, with an EC50 of 0.27 μM[1].

Product Specifications

CAS Number

[2305372-67-0]

Product Name Alternative

APC

UNSPSC

12352005

Target

Wnt

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/wnt-beta-catenin-agonist-1.html

Purity

99.72

Solubility

DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CCN1CC2=CC(OCC3=CC(C)=NN3C)=C(O)C=C2C4=C1C(C)=CC=C4

Molecular Formula

C22H25N3O2

Molecular Weight

363.45

References & Citations

[1]Chen DZ, et al. Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/β-catenin signalling pathway agonists. Bioorg Chem. 2019 Mar;84:285-294.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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