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Trans-Ned 19

Trans-Ned 19 is a pharmacological inhibitor that antagonizes NAADP receptors and blocks two-pore channels (TPCs) . It is used in research to suppress intracellular calcium signaling, as demonstrated by its inhibition of calcium signals in HUVECs and histamine-induced vasodilation in isolated rat aorta.

Product Specifications

CAS Number

1354235-96-3

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Purity

99.87% (May vary between batches)

Smiles

C (O) (=O) [C@@H]1CC2=C ([C@H] (N1) C3=CC (CN4CCN (CC4) C5=C (F) C=CC=C5) =C (OC) C=C3) NC=6C2=CC=CC6

Molecular Formula

C30H31FN4O3

Molecular Weight

514.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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