Trans-Ned 19
Trans-Ned 19 is a pharmacological inhibitor that antagonizes NAADP receptors and blocks two-pore channels (TPCs) . It is used in research to suppress intracellular calcium signaling, as demonstrated by its inhibition of calcium signals in HUVECs and histamine-induced vasodilation in isolated rat aorta.
Product Specifications
CAS Number
1354235-96-3
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
99.87% (May vary between batches)
Smiles
C (O) (=O) [C@@H]1CC2=C ([C@H] (N1) C3=CC (CN4CCN (CC4) C5=C (F) C=CC=C5) =C (OC) C=C3) NC=6C2=CC=CC6
Molecular Formula
C30H31FN4O3
Molecular Weight
514.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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