Norbinaltorphimine dihydrochloride
Norbinaltorphimine dihydrochloride is a selective, potent κ-opioid receptor (KOR) antagonist. It is widely used in neuroscience research to study KOR function, notably for inducing and investigating itch-related behaviors in murine models, as well as in vitro receptor binding assays.
Product Specifications
CAS Number
113158-34-2
Product Name Alternative
Norbinaltorphimine, nor-Binaltorphimine, Norbinaltorphimine dihydrochloride, Norbinaltorphimine Dihydrochloride, nor-Binaltorphimine Dihydrochloride, nor-Binaltorphimine dihydrochloride, Nor-Binaltorphimine dihydrochloride, nor-BNI, nor-BNI Dihydrochloride, nor-BNI dihydrochloride, Nor-BNI dihydrochloride, Opioid Receptor, OpioidReceptor, κ opioid receptor
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
≥98% (May vary between batches)
Solubility
H2O:20 mg/mL (27.22 mM) ; DMSO:80 mg/mL (108.89 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (4.49 mM)
Smiles
Cl.Cl.[H][C@@]12Oc3c4c (C[C@@]5 ([H]) N (CC6CC6) CC[C@@]14[C@@]5 (O) Cc1c4C[C@@]5 (O) [C@@]6 ([H]) Cc7ccc (O) c8O[C@@] ([H]) (c4[nH]c21) [C@]5 (CCN6CC1CC1) c78) ccc3O
Molecular Formula
C40H45Cl2N3O6
Molecular Weight
734.71
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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