NPD-1335
NPD1335 is a potent and selective inhibitor of Trypanosoma brucei phosphodiesterase B1 (TbrPDEB1) . Its submicromolar anti-parasitic activity stems from elevating intracellular cAMP, which disrupts the cell cycle. This mechanism makes it a valuable chemical tool for studying cAMP signaling in trypanosomes in both in vitro and in vivo research contexts.
Product Specifications
CAS Number
2376326-31-5
Field of Research
Infectious Disease & Virology, Metabolism Research
Smiles
[H][C@]12CC=CC[C@@]1 ([H]) C (=NN (C (C) C) C2=O) c1ccc (OC) c (c1) C#CC (=O) NCc1ccccc1
Molecular Formula
C28H29N3O3
Molecular Weight
455.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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