NSC117079
NSC117079 is a selective small molecule inhibitor of PHLPP1 and PHLPP2 phosphatases. By inhibiting these targets, it promotes AKT activation in neurons, offering protection against apoptotic cell death in models like staurosporine-treated cultures. This tool compound is useful for studying neuroprotection, AKT signaling pathways, and phosphatase function in both in vitro and in vivo research contexts.
Product Specifications
CAS Number
500363-63-3
Product Name Alternative
NSC117079, NSC-117079, NSC 117079
Field of Research
Metabolism Research
Purity
98.11% (May vary between batches)
Solubility
DMSO:40 mg/mL (84.48 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.22 mM)
Smiles
O=C1C=2C=CC=CC2C (=O) C3=C (C=C (C (N) =C13) S (=O) (=O) O) NC4=CC=CC (=C4) S (=O) (=O) N
Molecular Formula
C20H15N3O7S2
Molecular Weight
473.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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