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O-Propargyl-Puromycin

OP-Puro (O-Propargyl-Puromycin) is a puromycin-derived alkyne analog that potently inhibits protein synthesis. It is widely used in both in vitro and in vivo studies for click chemistry-based detection and quantification of newly synthesized proteins, facilitating research in translation, neurobiology, and cancer.

Product Specifications

CAS Number

1416561-90-4

Product Name Alternative

O Propargyl Puromycin, OP-puro, OPropargylPuromycin, O-Propargylpuromycin, O-Propargyl-Puromycin, protein synthesis

Purity

97.83% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.09 mM) ; DMSO:257.5 mg/mL (519.65 mM)

Smiles

CN (C) c1ncnc2n (cnc12) [C@@H]1O[C@H] (CO) [C@@H] (NC (=O) [C@@H] (N) Cc2ccc (OCC#C) cc2) [C@H]1O

Molecular Formula

C24H29N7O5

Molecular Weight

495.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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