OICR-0547

OICR-0547 is an inactive analog of the WDR5-MLL interaction inhibitor OICR-9429, serving as a critical negative control in biochemical and cellular assays. This compound is utilized in epigenetics and cancer research to validate the on-target effects of WDR5 inhibition in studies of mixed lineage leukemia and other malignancies.

Product Specifications

CAS Number

1801873-49-3

Product Name Alternative

OICR 0547, OICR0547, OICR-0547

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.37 mM) ; DMSO:180 mg/mL (331.77 mM)

Smiles

O=C1C=C (C (=CN1) C (=O) NC2=CC (=CC=C2N3CCOCC3) C=4C=CC=C (C4) CN5CCOCC5) C (F) (F) F

Molecular Formula

C28H29F3N4O4

Molecular Weight

542.55

Storage Conditions

-20°C

Notes

For research use only.

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